A STUDY ON THE IMPACT OF REGULAR PLATELET DONATION ON BLOOD FACTORS AND PLATELET REJUVENATION IN ATHLETES

Abstract

Objective: This study investigates the impact of physiological blood factors on platelet rejuvenation in athletes undergoing single platelet donation. The study aims to identify specific blood parameters that influence the efficacy of platelet recovery, which is crucial for maintaining optimal physiological functions in athletes, especially those involved in high-endurance sports. Methods: From March 2022 to March 2023, 120 single platelet donations were analyzed. Donors were randomly assigned into two groups, with 60 participants in each. This study focused on correlating various blood factors with the rate of platelet rejuvenation post-donation, utilizing both univariate and multivariate logistic regression analyses to determine the independent influencing factors. Results: The analysis identified hematocrit (HCT), red blood cell count (RBC), and lipid levels as significant independent risk factors affecting platelet rejuvenation. Elevated HCT and RBC levels were particularly noted to interfere with the efficacy of platelet separation, often leading to the contamination of the platelet product with red cells, a phenomenon known as "flushing." Conclusions: The findings highlight that specific blood parameters, such as HCT and lipid levels, significantly impact the recovery and quality of platelets post-donation in athletes. Managing these blood factors before donation can enhance the recovery rate of platelets, which is essential for athletes to maintain their performance and recovery capabilities. This study underlines the need for tailored donor management protocols that consider the unique physiological profiles of athlete donors to optimize post-donation platelet rejuvenation.