NURSING MANAGEMENT OF HORMONE PULSE THERAPY IN ATHLETES WITH PD-1 INHIBITOR-INDUCED IMMUNE PNEUMONIA AND TYPE II RESPIRATORY FAILURE

Abstract

Objective: To evaluate the effectiveness of personalized nursing care in the administration of hormone pulse therapy for athletes with immune-associated pneumonia complicated by type II respiratory failure induced by PD-1 inhibitors. Methods: This study involved 100 patients diagnosed with PD-1 inhibitor-related immune pneumonia and type II respiratory failure treated at our hospital from May 2022 to February 2023. Patients were randomly divided into two groups: an observation group (n=50) receiving personalized nursing care alongside hormone pulse therapy, and a control group (n=50) receiving standard nursing care with the same medical treatment. We assessed and compared both groups on various parameters, including blood gas levels, lung function tests (FEV1, FVC, FEV1/FVC), psychological health (Self-Rating Depression Scale [SDS], Self-Rating Anxiety Scale [SAS]), incidence of complications, and overall nursing satisfaction. Results: There were no significant differences in demographic data such as age, gender, and BMI between the two groups (P>0.05). The observation group exhibited significantly better outcomes in terms of improved blood gas measurements (higher PaO2 and SaO2, lower PaCO2), lung function (higher FEV1, FVC, and FEV1/FVC ratio), and lower scores on depression and anxiety scales (P<0.05). The rate of complications did not differ significantly between the groups, with fewer complications observed in the observation group, although this was not statistically significant (P>0.05). Notably, nursing satisfaction was significantly higher in the observation group (P<0.05). Conclusion: Personalized nursing care in the management of hormone pulse therapy for immune-associated pneumonia in athletes enhances clinical outcomes, stabilizes crucial physiological parameters, and significantly improves patient psychological well-being and satisfaction with care. This approach not only fosters better patient engagement and quality of life but also demonstrates the value of tailored nursing interventions in complex therapeutic scenarios involving athletes undergoing treatment for severe immune reactions induced by PD-1 inhibitors. This personalized care model is recommended for broader implementation to optimize treatment outcomes and patient experiences in similar clinical settings.