EVALUATING THE IMPACT OF STRUCTURED PHYSICAL ACTIVITY ON MENTAL HEALTH AND QUALITY OF LIFE IN PATIENTS WITH SEVERE BONE MARROW SUPPRESSION POST-CHEMOTHERAPY

Authors

  • Lili Jiang Department of Hematology, Affiliated Hospital of Jiangnan University, Wuxi City, Jiangsu Province, 214000, China
  • Junxue Hua Department of Hematology, Affiliated Hospital of Jiangnan University, Wuxi City, Jiangsu Province, 214000, China
  • Jingfen Zhou Department of Hematology, Affiliated Hospital of Jiangnan University, Wuxi City, Jiangsu Province, 214000, China
  • Yan Zhang Department of Hematology, Affiliated Hospital of Jiangnan University, Wuxi City, Jiangsu Province, 214000, China
  • Fang Teng Department of Hematology, Affiliated Hospital of Jiangnan University, Wuxi City, Jiangsu Province, 214000, China
  • Ting Xu Department of Hematology, Affiliated Hospital of Jiangnan University, Wuxi City, Jiangsu Province, 214000, China
  • Hongyun Cao Department of Hematology, Affiliated Hospital of Jiangnan University, Wuxi City, Jiangsu Province, 214000, China

Keywords:

Chemotherapy; Severe bone marrow suppression; Laminar flow ward; Depression and anxiety; Quality of life

Abstract

Objective: To analyze the depression, anxiety and quality of life of athletic patients with severe myelosuppression after chemotherapy in laminar flow ward. Methods: A total of 158 athletic patients with severe myelosuppression after chemotherapy in our hospital from March 2021 to April 2023 were randomly divided into an observation group and a control group, 79 cases in each group. The observation group received aseptic nursing in the laminar flow ward, while the control group received aseptic nursing in the conventional ward. The depression, anxiety and quality of life of the two groups were compared. Results: Compared with the control group, the observation group had a significantly longer onset time of fever, but a significantly lower duration of other clinical indicators (P < 0.05). Before the intervention, the depression scores and anxiety scores of the two groups were at a high level (P > 0.05). After the intervention, the scores of depression and anxiety in the two groups were significantly decreased, and those in the observation group were significantly lower (P < 0.05). Before the intervention, the scores of physiology, psychology, social relationship and environment of the two groups were all at a low level (P < 0.05). After intervention, the scores of all dimensions of quality of life in the two groups increased to varying degrees, and the scores of all dimensions in the observation group were higher than those in the control group (P < 0.05). There were 12 cases of infection in the observation group, with an infection rate of 15.19%, and 25 cases of infection in the control group, with an infection rate of 31.65%. The infection rate of the observation group was significantly lower than that of the control group (X2=5.964, P=0.015). Conclusion: The application of laminar flow ward can effectively relieve the depression and anxiety of athletic patients with severe bone marrow suppression after chemotherapy. It can not only optimize the ward environment, improve the comfort of athletic patients during hospitalization, but also strengthen the compliance of athletic patients in treatment, so as to improve the quality of life of athletic patients, prevent the occurrence of infection and improve the prognosis of athletic patients, which is worthy of clinical application.

 

Published

2024-07-26