EXPLORING THE POTENTIAL OF TRIM PROTEINS AS THERAPEUTIC TARGETS IN OVARIAN CANCER: IMPLICATIONS FOR ATHLETE HEALTH AND PERFORMANCE
Keywords:
Ovarian Cancer, TRIM Family, Carcinogenesis, Signaling Pathway, Target Therapy.Abstract
Ovarian cancer remains a significant health concern among female athletes, impacting their well-being and athletic performance. The Tripartite Motif (TRIM) family of proteins, known for their versatile roles in cellular processes such as proliferation, invasion, and metastasis, are pivotal in the progression of ovarian cancer. These proteins function as both oncogenes and tumor suppressors, influencing the pathogenesis of this malignancy. This review delves into the signaling pathways that TRIM proteins modulate, contributing to the onset and advancement of ovarian cancer, with a focus on implications for female athletes. Understanding the complex relationship between TRIM proteins and ovarian cancer not only aids in identifying potential therapeutic targets but also enhances the management strategies tailored specifically for athlete health, ensuring their return to peak performance post-treatment and maintaining their long-term health.