META-ANALYSIS OF THE EFFECTS OF DIFFERENT COGNITIVE INTERVENTION MODALITIES ON COGNITIVE FUNCTION IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT AFTER STROKE

Abstract

Objective: To explore the effect of 6 different cognitive training methods on mild cognitive impairment after stroke. Methods: Clinical Data were collected by searching PubMed, EMbase, Cochrane Library, SinoMed, WanFang Data, CNKI and other databases from the establishment of the database to September 2023. Two researchers respectively screened the literature, extracted data, assessed bias, and used Openbugs3.2.3 and Stata16.0 to process the data. Results: Thirty-seven studies were included, involving 3851 patients. The study found that: 5 cognitive interventions can significantly improve the cognitive function of mild cognitive impairment after stroke; Cognitive domain control SMD = 1.27, 95% CI (1.685, 0.91), P < 0.05] the best effect. Followed by cognitive training [SMD = 1.01, 95% CI (1.50, 0.52), P < 0.05), virtual reality training [SMD = 1.21, 95% CI (1.77, 0.61), P < 0.05), Noninvasive neuromodulation [SMD = 1.08, 95% CI (1.57, 0.61), P < 0.05], cognitive stimulation [SMD = 1.08, 95% CI (1.81, 0.06), P < 0.05). Conclusion: All five kinds of cognitive training can improve the cognitive function of patients with mild cognitive impairment after stroke, and the control of cognitive area is the best. However, further high-quality clinical trials are needed to confirm this.