MUSCLE POWER AND BLOOD LACTATE KINETICS IN ACTN3 GENOTYPES

Authors

  • Güereca-Arvizuo, J PhD in Physical Activity Sciences. Professor. Department of Health Sciences. Multidisciplinary Division at Ciudad Universitaria. Autonomous University of Ciudad Juarez (Mexico)
  • Hernández-Torres, P PhD in Sciences. Professor. Faculty of Physical Activity Sciences, Autonomous University of Chihuahua (Mexico)
  • Moreno-Brito, V PhD in Experimental Pathology. Professor. Faculty of Medicine and Biomedical Sciences. Autonomous University of Chihuahua (Mexico)
  • Sierra-Muñiz, G PhD in Sciences. Professor. Department of Health Sciences, Institute of Biomedical Sciences. Autonomous University of Ciudad Juarez (Mexico)
  • Trejo-Trejo, M PhD in Medical Sciences. Professor. Faculty of Sports. Autonomous University of Baja California (Mexico)
  • Cervantes-Borunda, M PhD in Sciences. Professor. Faculty of Physical Activity Sciences. Autonomous University of Chihuahua (Mexico)
  • Ramos-Jiménez, A Corresponding author. PhD in Sciences. Professor. Department of Health Sciences, Institute of Biomedical Sciences. Autonomous University of Ciudad Juarez (Mexico)

Keywords:

Alpha-actinin-3, lactate dehydrogenase, sport genetics, sport performance, R577X polymorphism

Abstract

In this study, the differences in muscle power and blood lactate concentration ([LA- ]b) kinetics among ACTN3 genotypes were examined during the Wingate anaerobic test (WAnT). Thirty-five healthy and physically active men (18-35 years old) volunteered to participate in the study. Muscle power, [LA- ]b concentration and Lactate Dehydrogenase (LDH) activity were analyzed. ACTN3 gene was determined from white blood cell DNA in peripheral blood. Regardless of the participants' body weight or muscle mass, RR genotype carriers developed greater muscle power during Want (p<0.05) than RX or XX genotypes, suggesting that RR genotype has greater capacity to use the ATP-PC system during supramaximal exercise. Muscle power and [LA-]b kinetics were similar in all genotypes. The Want was not sufficient to make muscle damage be detected in LDH concentration.

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Published

2023-10-16

Issue

Vol. 22 No. 86 (2022): Vol. 22, nº 86, junio/June 2022

Section

Articles