EFFECTS OF ACUPUNCTURE AND 5-HT3 RECEPTOR ANTAGONISTS ON MAINTAINING PHYSICAL ACTIVITY IN ATHLETES UNDERGOING CHEMOTHERAPY FOR CINV
Keywords:
acupuncture; 5-HT3 receptor antagonist; CINV;Tumor chemotherapyAbstract
Objective: To evaluate the therapeutic effects and the commonly used acupoint selection scheme of acupuncture combined with anti-emetic drugs on CINV after chemotherapy in athletic patients. Methods: a systematic review of the existing randomized controlled trials of acupuncture combined with western medicine in the treatment of vomiting and hiccup in athletic patients after chemotherapy. The meta-analysis was conducted by Revman 5.3 software. Results: a total of 13 related literatures were included in this study, including 824 athletic patients with nausea and vomiting after chemotherapy, including 413 cases in the observation group and 411 cases in the control group. Meta analysis showed that the total effective rate of the observation group was higher than that of the control group [RR=1.27,95%CI (1.18, 1.37), P<0.00001]. Conclusion: Compared with conventional treatments, acupuncture combined with western medicine can improve the curative effect on vomiting and hiccup symptoms of tumor patients after chemotherapy, but due to the limitations of the number and quality of included studies, the above conclusions need to be verified by more high-quality studies.