EXPLORING THE LINK BETWEEN TYPE 2 DIABETES AND CEREBRAL INFARCTION RISK IN ELDERLY ATHLETES: THE ROLE OF GLUCOSE AND LIPID METABOLISM DISORDERS

Abstract

Objective: This study aims to evaluate the risk factors for cerebral infarction in elderly patients with Type 2 Diabetes Mellitus (T2DM) and their connection to glucose and lipid metabolic disturbances. Methods: A retrospective study was conducted on elderly T2DM patients at our hospital from January 2020 to January 2022. Patients were divided based on MRI outcomes into those with cerebral infarction (observation group) and those without (control group). We analyzed patient demographics, medical history, biochemical markers on admission, and outcomes to discern risk factors. Glucose and lipid metabolism were assessed, including markers like glycosylated hemoglobin (HbA1c), fasting blood glucose (FBG), total cholesterol (TC), triglycerides (TG), LDL cholesterol (LDL-C), and HDL cholesterol (HDL-C). Results: The observation group showed significantly higher levels of FBG, TC, TG, and LDL-C, with decreased HDL-C compared to controls (P<0.05). A positive correlation was noted between cerebral infarction severity and increases in systemic blood pressures, TC, TG, and LDL-C. Multivariate analysis identified high HbA1c, TC, and LDL-C levels as significant predictors of cerebral infarction risk (P<0.05). The ROC curve analysis underscored the predictive value of these markers for cerebral infarction in T2DM patients. Conclusion: Elevated levels of HbA1c, LDL-C, and TC significantly heighten the risk of cerebral infarction in elderly T2DM patients. Monitoring these metabolic parameters may provide critical insights into the severity and risk management of cerebral infarction in this patient population, enhancing early diagnostic and therapeutic strategies.