EVALUATING SERUM CK, CK-MB, AND CTNT AS BIOMARKERS FOR ACUTE GESTATIONAL HYPERTENSION IN PREGNANT ATHLETES

Authors

  • Zheng Jun’e Department of Obstetrics, Zibo Central Hospital, Zibo, 255000, China.
  • Shao Meiqin Physical examination Center of Zibo Central Hospital, Zibo, 255000, China.
  • Zhao Qiang Department of General Medicine, Zibo Central Hospital, Zibo, 255000, China.
  • Sun Fengtao Department of Obstetrics, Zibo Central Hospital, Zibo, 255000, China.

Keywords:

Pre-eclampsia; serum creatine kinase; serum creatine kinase isoenzyme; cardiac troponin T; diagnosis; prediction

Abstract

To explore the diagnostic significance of serum creatine kinase (CK), creatine kinase-MB (CK-MB), and cardiac troponin T (cTnT) in hypertensive disorders among pregnant athletes. Methods: This study involved a cohort of pregnant athletes diagnosed with hypertensive disorders and a control group of healthy pregnant athletes. Serum samples were collected during the second trimester and analyzed for levels of CK, CK-MB, and cTnT using electrochemiluminescence immunoassay. Results: Elevated levels of CK, CK-MB, and cTnT were observed in the group with hypertensive disorders compared to controls. Diagnostic sensitivity and specificity were calculated, revealing high efficacy of these markers in predicting hypertensive conditions. Conclusion: The elevated biomarkers CK, CK-MB, and cTnT can effectively diagnose and differentiate hypertensive disorders in pregnant athletes, offering a reliable tool for early intervention and management strategies tailored to this unique population.

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Published

2024-03-01

Issue

Vol. 24 No. 95 (2024): Vol. 24, No. 95, marzo/March 2024

Section

Manuscript