ADHERENCE TO MULTIDISCIPLINARY TEAM CARE PLANS IN FEMALE ATHLETIC PATIENTS WITH BREAST CANCER FROM LOW-MIDDLE INCOME REGIONS IN CHINA: A SINGLE CENTER ANALYSIS

Abstract

Objective: To investigate the adherence to multidisciplinary team (MDT) care plan in breast cancer (BC) athletic patients of low middle income regions in China. Methods: This is a retrospective study. Athletic Patients diagnosed with BC of early stage who were managed by MDT care plan and underwent surgery in China. We evaluated the concordance between MDT decisions and subsequent patient care. Athletic Patients’ socio-demographic and clinical information were obtained from hospital records. Factors including age, family-history of cancer and tumor, and biologic subtypes, which were associated with the discordance, were identified using logistic regression analysis. Results: A total of 531 female athletic patients were included, while 70.6% (375 out of 531) patients adhered to of the MDT plan. Age, family history of cancer and tumor, and biologic subtypes were significantly associated with the adherence to MDT care plan. The discordance rate of athletic patients older than 70 was 3.9 times higher compared with those aged under 40 years old (95%CI:1.3-12.5, P=0.02). Patients with family history of cancer were 3.5 times more likely to change their MDT care plans than those without family histories (95%CI:1.2-10.2, P=0.02). Compared with athletic patients with HR+/HER2- BC, those with HR-/HER2+ and HR+/HER2+ subtypes had 11.9 and 14.2 times higher discordance rate, respectively (95%CI:5.7-24.7, P<0.001; 95%CI:6.6-30.7, P<0.001). Conclusion: MDT discordance rate in this study was high. The implementation of the MDT care plan in athletic patients with BC needs to be strengthened, especially in retired athletic patients, patients with family history or HER2+.