FACTORS INFLUENCING THE RATE OF RESIDUAL STENOSIS IN ATHLETIC PATIENTS AFTER ENDOVASCULAR INTERVENTION FOR SYMPTOMATIC CAROTID ARTERY STENOSIS

Authors

  • Yi Quan Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China
  • Ao-fei Liu Division of Life Science Metrology, National Institute of Metrology, Beijing, 100013, China
  • Chen Li Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China
  • You-xun Jin Division of Life Science Metrology, National Institute of Metrology, Beijing, 100013, China
  • Yun-e Liu Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China
  • Ji Zhou Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China
  • Su-san Hu Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China
  • Xiao-xiao Yin Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China
  • Xia Li Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China, Division of Life Science Metrology, National Institute of Metrology, Beijing, 100013, China
  • Min Jin Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China
  • Jin Lv Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China, Central Laboratory of Research Department, The PLA Rocket Force Characteristic Medical Center, Beijing, 100088, China
  • Wei-jian Jiang Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China

Keywords:

symptomatic carotid artery stenosis, endovascular intervention, postoperative residual stenosis rate, neutrophil-to-lymphocyte ratio, clopidogrel

Abstract

Objective: High residual stenosis after endovascular treatment was a risk factor for postoperative stenosis in athletic patients with symptomatic carotid artery stenosis. This study investigated the factors influencing the residual stenosis rate after endovascular interventional therapy for symptomatic carotid artery stenosis.

Methods: This study involved 337 athletic patients with symptomatic carotid artery stenosis (191 in a residual stenosis group and 186 in a non-residual stenosis group). To obtain differences in distribution between residual and non-residual stenosis groups, the variables of baseline information were dichotomized by median value and compared by chi-square test. In addition, we screened the categorical variables for each risk factor by a single-factor linear regression model and then determined the final influencing factors by the stepwise regression model.

Results: Among the 377 athletic patients with symptomatic carotid artery stenosis, 191 (50.66%) developed residual stenosis after interventional recanalization procedures. Analysis of single-factor linear regression model showed that age and NLR were statistically significant (P<0.05) even during the continuous change in residual stenosis rate, and there was a positive correlation between them. Stepwise regression analysis showed that age and NLR were positive correlated with the occurrence of residual stenosis after excluding possible confounding factors, which was consistent with the results of the single-factor linear regression model (P<0.05).

Conclusion: NLR, as a notable predictor of inflammation, had an important predictive value for the occurrence of residual stenosis after EVT. In addition, age of athletic patients also increased the risk of residual stenosis to some extent.

Downloads

Published

2023-05-01

Issue

Vol. 23 No. 89 (2023): Vol. 23, No. 89, marzo/March 2023

Section

Articles