The purpose of the study was to assess the effect of physical health on the learning experience of athletes (SLE). Furthermore, the mediating and moderating roles of quality of life (PQOL), physical self-esteem (PSE), and physical health impairments were studied. The study utilized the quantitative research methodology and cross-sectional design. The study's primary respondents were the athletes who were picked using a simple sampling procedure. For data collection, the self-administered survey questionnaire was employed. The results of the Partial Least Square (PLS)-Structural Equation Modeling (SEM) reveal that physical activity (PA) has a favorable and statistically significant impact on sportsman LE, PQOL, and PSE. PA has beneficial and strong impacts on SLE, both as a mediator and as a moderator. Consequently, based on the findings mentioned above, the current study provided a body of literature to the existing literature about the moderating and mediating impact, which might contribute to the expansion of research in this particular field. The findings of this study may help advise university policymakers on the benefits of physical activity in increasing student productivity.