Background The research aims to determine the outcomes of single or multilevel ACDF with polietereterketon (PEEK) cages in 152 patients (237 cages) with a focus on the cage instability in terms of migration and subsidence that may occur in the early postoperative period. Method 176 consecutive patients who had undergone single-or multilevel anterior cervical discectomy with PEEK cage for cervical syndolysis (CDDH) from January 2015 to January 2021 were retrospective evaluated.152 patients (237 PEEK cages) who were found to be suitable for the study criteria were included. Results Cage migration was observed in 15 cages in 12 patients without relevant clinical complaints. There was no case of superior migration of the cage into the superior end plate and no posterior or sideways migration. Subsidence was not detected in any cage, and functional radiological examination was present in all cases with maintained intervened disc distance height during the follow-ups. Discussion and conclusion: PEEK cages without anterior plate instrumentation and using postoperative neck collars in single-level and multilevel ACDF provide reliable and valid clinical and radiological results