Objective: To explore the application of humanized nursing and psychotherapy concept in the management of mental health care and its impact on patient relations, so as to establish a harmonious relationship and improve the quality of nursing and psychotherapy. Methods: From May 2021 to March 2021, 110 psychiatric patients were clustered into follow-up and control group. The team adopted the conventional nursing and psychotherapy mode and added a more humanized nursing and psychotherapy mode based on team nursing. The two groups were compared in their satisfaction with medical services, nursing dependence, nursing errors, psychotherapy and nursing disputes. Conclusion: The humanistic nursing model for patients is helpful to improve nursing satisfaction and dependence, reduce the incidence of poor nursing and psychotherapy on patients