The variation in strength may have been caused by qualitative differences in the muscle tissue, such as a higher concentration of glycolytic enzymes and a more significant proportion of fast-type muscle fibres, even though the number of muscle fibres did not change statistically significantly between the genders studied. It is well known that men possess a larger muscular mass than women, which is packed with fast-type fibres, and a higher capacity for glycolysis. The study ascertains how gender differs in the hormonal and neuromuscular responses to strength training. Based on research, primary data analysis is used to gather data using SPSS software, which is then used to provide findings for the ANOVA test, correlation, and paired sample test between the data. The gender difference in power may be influenced by aspects related to anthropometry, task-specificity, and the anatomical characteristics of muscles. More recent studies, however, have shown that the muscle mass in the lower limbs of both men and women was normalised to provide similar amounts of power. Numerous neuromuscular parameters, such as muscle morphological traits including thickness, fascicle length, and pennation angle, affect maximal strength and power. Recent studies have revealed tenuous relationships between the vastus lateralis muscle architecture in resistance-trained people and the maximal isometric force applied at the mid-shin pull. Furthermore, a strong relationship was found between the vastus intermedius muscle's architecture and the late phase of the force generation rate during isometric leg extension. Further investigation showed shown a high correlation between peak power and the duration required to attain peak power in the Wingate test, as well as the architecture of the vastus lateralis muscle. Overall, the findings indicated a clear connection between gender variations and hormonal and neuromuscular insights.